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Herein we discuss the potential consequences of altered miR expression in CF airway epithelium particularly with respect to cystic fibrosis transmembrane conductance regulator (cftr) expression, innate immunity and toll-like receptor signalling and explore how best to exploit these changes for therapeutic benefit.

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Ward-Caviness CK, Kraus WE, Blach C, Haynes CS, Dowdy E, Miranda ML, Devlin RB, Diaz-Sanchez D, Cascio WE, Mukerjee S, Stallings C, Smith LA, Gregory SG, et al. Association of Roadway Proximity with Fasting Plasma Glucose and Metabolic Risk Factors for Cardiovascular Disease in a Cross-Sectional Study of cardiac catheterization patients.

He was an elegant man in very plain evening dress; tall, but with an air of not taking up much room; one felt that he could have slid along like a shadow where many smaller men would have been obvious and obstructive. His face, now flung back in the lamplight, was swarthy and vivacious, the face of a foreigner.

William S. Summit was a member of Albany, Oregon, Chapter 585. John K. Suntken , 59, was an at-large member of Michigan. Robert Lawrence Swanson , 72, died November 4, 2006, from pulmonary fibrosis and respiratory failure.

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Independently another group provided more evidence for a role for miR-101 (and miR-144, each of which binds to the same site in the CFTR 3’UTR) in regulation of CFTR mRNA and protein expression , however they suggested that these miRs may have a role in cigarette-smoke-induced inhibition of CFTR in the context of chronic obstructive pulmonary disease.

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